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acute myeloid leukemia 7

acute promyelocytic leukemia 7

failure mechanism 6

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liver transplantation 6

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acute lymphoblastic leukemia 4

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Assessment of liver volume variation to evaluate liver function

Cong Tong, Xinsen Xu, Chang Liu, Tianzheng Zhang, Kai Qu

Frontiers of Medicine 2012, Volume 6, Issue 4,   Pages 421-427 doi: 10.1007/s11684-012-0223-5

Abstract:

In order to assess the value of liver volumetry in cirrhosis and acute liver failure (ALF) patientsto get a regression formula for standard liver volume (SLV) and BSA.In conclusion, the CTLV/SLV ratio, which reflects liver volume variations, correlates well with the liverfunction and progression of cirrhosis and ALF.It is also a very useful marker for predicting the prognosis of ALF.

Keywords： liver volume variation     cirrhosis     acute liver failure (ALF)    

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Overview on acute-on-chronic liver failure

Jing Zhang,Shan Gao,Zhongping Duan,Ke-Qin Hu

Frontiers of Medicine 2016, Volume 10, Issue 1,   Pages 1-17 doi: 10.1007/s11684-016-0439-x

Abstract:

Liver failure (LF) is defined as severe dysfunction in hepatic synthesis, detoxification, and metabolismLF can be classified into acute LF, acute-on-chronic LF (ACLF), and chronic LF.

Keywords： liver failure     chronic liver failure     acute-on-chronic liver failure     diagnosis     prognosis     treatment    

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Comprehensive treatment of acute-on-chronic liver failure in a patient with hepatitis B: a case report

Lei Li,Yimei Liu,Tiancheng Luo,Jian Zhou,Yingyong Hou,Xizhong Shen,Jiyao Wang

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 250-253 doi: 10.1007/s11684-014-0333-3

Abstract:

The clinical data of a patient with acute-on-chronic liver failure were analyzed retrospectively.His liver function deteriorated, yielding Child-Pugh grade C and reaching a model for end-stage liverperiod; this condition was complicated with highly active variceal bleeding and coagulation system failurePiggyback orthotopic liver transplantation was performed as the final treatment.

Keywords： acute-on-chronic liver failure     submassive necrosis     viral hepatitis B     esophageal variceal bleeding     liver    

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Bioartificial liver devices: Perspectives on the state of the art

Yi-Tao DING, MM, Xiao-Lei SHI, MD

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 15-19 doi: 10.1007/s11684-010-0110-x

Abstract:

Acute liver failure remains a significant cause of morbidity and mortality.Bioartificial liver (BAL) devices have been in development for more than 20 years.patients’ own liver has recovered or a donor liver becomes available for transplant.In conclusion, BAL is, in principle, an important therapeutic strategy for patients with acute liverfailure, and may also be a bridge to liver transplantation.

Keywords： acute liver failure     bioartificial livers     hepatocyte     bioreactor    

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Intra-abdominal hypertension is an independent cause of acute renal failure after orthotopic liver transplantation

SHU Ming, PENG Chenghong, CHEN Hao, SHEN Boyong, ZHOU Guangwen, SHEN Chuan, LI Hongwei

Frontiers of Medicine 2007, Volume 1, Issue 2,   Pages 167-172 doi: 10.1007/s11684-007-0031-5

Abstract: An independent association between acute renal failure (ARF) and intra-abdominal hypertension (IAH) afterliver transplantation has not been established previously.This study involved 62 subjects who underwent liver transplantation.IAH impaired renal function and was an independent risk factor for ARF after liver transplantation.
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The “Traditional Chinese medicine regulating liver regeneration” treatment plan for reducing mortalityof patients with hepatitis B-related liver failure based on real-world clinical data

Ling Dai, Xiang Gao, Zhihua Ye, Hanmin Li, Xin Yao, Dingbo Lu, Na Wu

Frontiers of Medicine 2021, Volume 15, Issue 3,   Pages 495-505 doi: 10.1007/s11684-020-0790-9

Abstract: explore the effect and mechanisms of the treatment plan of “traditional Chinese medicine (TCM) regulating liverA total of 457 patients with HBV-related liver failure were retrospectively collected.In addition, there were significant differences in the expression of several cytokines related to liverRLR treatment can decrease jaundice, improve liver function, and significantly reduce the mortality inpatients with HBV-related liver failure.

Keywords： hepatitis B virus-related liver failure     traditional Chinese medicine     liver regeneration     liver regeneration    

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Gut Microbiota-Controlled Tryptophan Metabolism Improves D-Gal/LPS-Induced Acute Liver Failure in C57BL Article

Zhipeng Zheng, Li Wu, Yuqiu Han, Jun Chen, Shuai Zhu, Yuanyuan Yao, Baohong Wang, Lanjuan Li

Engineering 2022, Volume 14, Issue 7,   Pages 134-146 doi: 10.1016/j.eng.2020.12.013

Abstract:

Acute liver failure (ALF) has an abrupt onset with a frequently fatal outcome.Previous studies have found that oral antibiotics prevent drug-induced liver injury in animal experimentssequencing showed that inflammatory responses were inhibited and metabolic pathways were upregulated in the liverof Abx-treated ALF mice., indicating that AhR directly regulated susceptibility to ALF, at least in part.

Keywords： Gut microbiota     Antibiotic     Tryptophan     Kynurenine     Aryl hydrocarbon receptor     Acute liver failure    

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Clinical analysis of 275 cases of acute drug-induced liver disease

LI Lei, JIANG Wei, WANG Jiyao

Frontiers of Medicine 2007, Volume 1, Issue 1,   Pages 58-61 doi: 10.1007/s11684-007-0012-8

Abstract: analyze the causative drugs, clinical manifestation and pathological characteristics of the patients with acutedrug-induced liver disease, from January 2000 to December 2005, 275 cases diagnosed as acute drug-inducedIn 41 cases, the diagnosis was confirmed by liver biopsy.The proportion of acute drug-induced liver disease among all of the acute liver injuries was annuallyThe most common drugs which induced acute liver injuries were traditional Chinese herb medicine (23.3%
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Gut microbial balance and liver transplantation: alteration, management, and prediction

Xinyao Tian, Zhe Yang, Fangzhou Luo, Shusen Zheng

Frontiers of Medicine 2018, Volume 12, Issue 2,   Pages 123-129 doi: 10.1007/s11684-017-0563-2

Abstract:

Liver transplantation is a conventional treatment for terminal stage liver diseases.Intestinal barrier destruction is widely observed among patients receiving liver transplant and sufferingThis article reviews the research progress for gut microbial alterations and liver transplantation.microbial alteration and the prediction of possible injuries utilizing microbial alteration during liverand offer a hypothesis on the utilization of microbial alteration in liver transplantation.

Keywords： gut microbial balance     liver transplantation     ischemia–reperfusion     acute rejection    

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Treatment of infant postrenal acute renal failure following obstruction due to upper urinary calculi

Hui-Xia ZHOU MD, Zhi-Chun FENG MD, Hao MENG MD, Xiao-Guang ZHOU MD, Shuang LI BM, Jun WANG MM, Shi-Xi DAI BM,

Frontiers of Medicine 2010, Volume 4, Issue 1,   Pages 127-130 doi: 10.1007/s11684-010-0009-6

Abstract: The surgical emergency treatments and curative effects of postrenal acute renal failure following obstructionOf the 13 infants with postrenal acute renal failure following obstruction due to upper urinary calculicatheterization of the ureter with ureteroscopy is a minimally invasive, safe and effective therapy for postrenal acuterenal failure following obstruction due to upper urinary calculi in infants.

Keywords： infant     acute renal failure     postrenal     ureteroscopy    

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Severe hepatoxicity caused by aspirin overdose: a case report

Zhuping Cao,Shiqi Liu,Jianhua Niu,Bing Wei,Jie Xu

Frontiers of Medicine 2015, Volume 9, Issue 3,   Pages 388-391 doi: 10.1007/s11684-015-0398-7

Abstract: A computed tomography (CT) scan showed evidence of bilateral inferior pulmonary infection and acute pancreatitisTwo years later, the patient died of chronic liver failure.

Keywords： aspirin     side effects     liver failure    

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Rdh13 deficiency weakens carbon tetrachloride-induced liver injury by regulating Spot14 and Cyp2e1 expression

Xiaofang Cui, Benting Ma, Yan Wang, Yan Chen, Chunling Shen, Ying Kuang, Jian Fei, Lungen Lu, Zhugang Wang

Frontiers of Medicine 2019, Volume 13, Issue 1,   Pages 104-111 doi: 10.1007/s11684-017-0568-x

Abstract: We previously generated knockout mice and showed that Rdh13 deficiency causes severe acute retinaleffect of Rdh13 on liver injury induced by carbon tetrachloride (CCl ).Although Rdh13 deficiency showed no significant effect on liver histology and physiological functionsunder regular culture, the mice displayed an attenuated response to CCl -induced liver injury.Furthermore, the mice had Rdh13 deficiency and thus their liver cells were protected from apoptosis

Keywords： retinol dehydrogenase 13     carbon tetrachloride     acute liver injury     Cyp2e1     Spot14    

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Partial liver transplantation

Nianqiao GONG, Xiaoping CHEN

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 1-7 doi: 10.1007/s11684-010-0105-7

Abstract:

Partial liver transplantation, including reduced-size liver transplantation, split liver transplantation, and living donor liver transplantation, has been developed with several innovative techniques becauseSplit liver transplantation provides chances to two or even more recipients when only one liver graftBefore surgery, a series of donor evaluations—including anatomical, liver volume, and liver functionAt different recipient conditions, auxiliary liver transplantation and auxiliary partial orthotopic liver

Keywords： partial liver transplantation     reduced-size liver transplantation     split liver transplantation     living donorliver transplantation    

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γδ T cells in liver diseases

Xuefu Wang, Zhigang Tian

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 262-268 doi: 10.1007/s11684-017-0584-x

Abstract: γδ T cells are enriched in the liver and exhibit liver-specific features.fatty liver disease, autoimmune hepatitis, liver fibrosis and cirrhosis, and liver cancer and regenerationWe believe that determining the properties and functions of γδ T cells in liver diseasesenhances our understanding of the pathogenesis of liver diseases and is useful for the design of novelγδ T cell-based therapeutic regimens for liver diseases.

Keywords： γδT cells     liver infection     non-alcoholic fatty liver disease     autoimmune hepatitis     liver fibrosis and cirrhosis     liver cancer     liver regeneration    

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NKT cells in liver diseases

Shasha Zhu, Huimin Zhang, Li Bai

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 249-261 doi: 10.1007/s11684-018-0622-3

Abstract: innate-like and tissue-resident lymphocytes, which recognize lipid antigens and are enriched in the livernatural killer T cells and their roles in hepatitis B virus and hepatitis C virus infection, autoimmune liverdiseases, alcoholic liver disease, nonalcoholic fatty liver disease, and hepatocellular carcinoma.and indicate the dynamic alteration in the role of natural killer T cells during the progression of liver

Keywords： natural killer T cells     hepatitis B virus and hepatitis C virus infection     autoimmune liver diseases     alcoholicliver disease     nonalcoholic fatty liver disease     hepatocellular carcinoma    

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Title Author Date Type Operation

Assessment of liver volume variation to evaluate liver function

Cong Tong, Xinsen Xu, Chang Liu, Tianzheng Zhang, Kai Qu

Journal Article

Overview on acute-on-chronic liver failure

Jing Zhang,Shan Gao,Zhongping Duan,Ke-Qin Hu

Journal Article

Comprehensive treatment of acute-on-chronic liver failure in a patient with hepatitis B: a case report

Lei Li,Yimei Liu,Tiancheng Luo,Jian Zhou,Yingyong Hou,Xizhong Shen,Jiyao Wang

Journal Article

Bioartificial liver devices: Perspectives on the state of the art

Yi-Tao DING, MM, Xiao-Lei SHI, MD

Journal Article

Intra-abdominal hypertension is an independent cause of acute renal failure after orthotopic liver transplantation

SHU Ming, PENG Chenghong, CHEN Hao, SHEN Boyong, ZHOU Guangwen, SHEN Chuan, LI Hongwei

Journal Article

The “Traditional Chinese medicine regulating liver regeneration” treatment plan for reducing mortalityof patients with hepatitis B-related liver failure based on real-world clinical data

Ling Dai, Xiang Gao, Zhihua Ye, Hanmin Li, Xin Yao, Dingbo Lu, Na Wu

Journal Article

Gut Microbiota-Controlled Tryptophan Metabolism Improves D-Gal/LPS-Induced Acute Liver Failure in C57BL

Zhipeng Zheng, Li Wu, Yuqiu Han, Jun Chen, Shuai Zhu, Yuanyuan Yao, Baohong Wang, Lanjuan Li

Journal Article

Clinical analysis of 275 cases of acute drug-induced liver disease

LI Lei, JIANG Wei, WANG Jiyao

Journal Article

Gut microbial balance and liver transplantation: alteration, management, and prediction

Xinyao Tian, Zhe Yang, Fangzhou Luo, Shusen Zheng

Journal Article

Treatment of infant postrenal acute renal failure following obstruction due to upper urinary calculi

Hui-Xia ZHOU MD, Zhi-Chun FENG MD, Hao MENG MD, Xiao-Guang ZHOU MD, Shuang LI BM, Jun WANG MM, Shi-Xi DAI BM,

Journal Article

Severe hepatoxicity caused by aspirin overdose: a case report

Zhuping Cao,Shiqi Liu,Jianhua Niu,Bing Wei,Jie Xu

Journal Article

Rdh13 deficiency weakens carbon tetrachloride-induced liver injury by regulating Spot14 and Cyp2e1 expression

Xiaofang Cui, Benting Ma, Yan Wang, Yan Chen, Chunling Shen, Ying Kuang, Jian Fei, Lungen Lu, Zhugang Wang

Journal Article

Partial liver transplantation

Nianqiao GONG, Xiaoping CHEN

Journal Article

γδ T cells in liver diseases

Xuefu Wang, Zhigang Tian

Journal Article

NKT cells in liver diseases

Shasha Zhu, Huimin Zhang, Li Bai

Journal Article